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1.1 Genomics, genetic basis of disease, HLA/T cell recognition
Author(s) -
Mok, MY,
Hahn, BH,
Guthridge, JM,
Arnett, FC,
Wang, J,
Song, YW,
Harley, JB,
Kaufman, KM,
Bae, SC,
Grossman, JM,
Qian, XX,
Zhao, J,
Yu, Y,
Fu, Q,
Howe, HS,
Shen, N,
Tsao, BP
Publication year - 2010
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/j.1756-185x.2010.01486.x
Subject(s) - medicine , league , citation , library science , computer science , physics , astronomy
Basic and Translational Research: 1.1 Genomics, genetic basis of disease, HLA/T cell recognitionOBJECTIVE: Previous genome wide association study conducted in a population of European ancestry identified rs4963128, a KIAA1542 SNP 23kb telomeric to IRF7, in strong association with SLE. This study was undertaken to investigate whether genetic polymorphism within IRF7 is a risk factor for the development of SLE. METHODS: A total of 5024 individuals from multiple ethnic groups …link_to_OA_fulltextThe 14th Congress of Asia Pacific League of Associations for Rheumatology, Hong Kong, China, 11-15 July 2010. In International Journal of Rheumatic Diseases, 2010, v. 13 suppl. 1, p. 9, abstract no. 069