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Type B insulin resistance in a systemic lupus erythematosus patient
Author(s) -
OSTWAL Vikas,
OAK Jyotsna
Publication year - 2009
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/j.1756-185x.2009.01402.x
Subject(s) - medicine , acanthosis nigricans , insulin resistance , insulin , antibody , type 2 diabetes , lupus erythematosus , immunology , endocrinology , systemic lupus , insulin receptor , diabetes mellitus , disease
In type B insulin resistance and acanthosis nigricans, the insulin resistance is due to the presence of anti‐insulin receptor antibody 1. Approximately one‐third of patients with these antibodies have an associated illness such as systemic lupus erythematosus (SLE) or Sjögren's syndrome. This report describes a case wherein the patient had presented with uncontrolled diabetes and required > 3000 units of human insulin to control hyperglycemia. She also had features of SLE. There was complete recovery following treatment with steroids.