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Tetracyclines: what a rheumatologist needs to know?
Author(s) -
ATTAR Suzan M.
Publication year - 2009
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/j.1756-185x.2009.01389.x
Subject(s) - medicine , tetracycline , antibiotics , acne , intensive care medicine , dermatology , broad spectrum , microbiology and biotechnology , chemistry , combinatorial chemistry , biology
Tetracyclines are broad‐spectrum antibiotics that act at the ribosomal level. They were first introduced in 1948 and were widely prescribed by dermatologists in the early 1950s for treatment of acne. More recently, biologic actions of tetracyclines affecting inflammation, angiogenesis, and bone metabolism have been researched. The therapeutic effects of tetracycline and its analogues in rheumatic diseases have also been investigated. This article will review the rheumatological use of tetracycline and its analogues.