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ACUTE KIDNEY INJURY IN CRITICALLY ILL A(H1N1)‐INFECTED PATIENTS: A STUDY OF THE PROGNOSES
Author(s) -
Chaari Anis,
Dammak Hssan,
Chtara Kamilia,
Bahloul Mabrouk,
Bouaziz Mounir
Publication year - 2011
Publication title -
journal of renal care
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.381
H-Index - 27
eISSN - 1755-6686
pISSN - 1755-6678
DOI - 10.1111/j.1755-6686.2011.00224.x
Subject(s) - medicine , acute kidney injury , multivariate analysis , organ dysfunction , risk factor , critically ill , respiratory distress , shock (circulatory) , acute respiratory distress , surgery , sepsis , lung
SUMMARY Purpose: to identify factors correlated with poor outcome and factors correlated with acute kidney injury (AKI) onset in critically A(H1N1) infected patients. Methods: All patients admitted for respiratory distress due to a confirmed infection by A(H1N1) virus were included retrospectively. Results: Thirty‐four patients were included. Mean age was 37.3 ± 20.8 years. Independent factors correlated to mortality in multivariate analysis were shock [OR = 32.52, CI95% (1.29–816.3); p = 0.034], AKI [OR = 31.12, CI95% (1.3–746.5); p = 0.034] and hyperglycaemia over than 5.7 mmol/l on admission [OR = 74, CI95% (1.01–5495); p = 0.049]. Only age over 30 years was identified as an independent factor correlated with the onset of AKI [OR = 18, CI95% (1.04‐312.41); p = 0.047] in multivariate analysis. Conclusion: AKI, as well as hypotension, is an independent factor correlated with mortality. Its onset is usually linked to multi‐organ failure. Advanced age is an important risk factor for renal dysfunction in this group of patients.