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Effects of technical and biological factors on the dynamic vessel analysis
Author(s) -
Klee Sascha
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2019.8281
Subject(s) - flicker , neurovascular bundle , retinal , blood flow , neuroscience , computer science , medicine , biology , ophthalmology , surgery , cardiology , operating system
Retinal arterioles and venules dilate when stimulated with flickering light. This phenomenon is described as functional hyperemia and closely associated with neurovascular coupling. The flicker causes a short period of heightened cellular metabolism which increases the need for blood. As a result the retinal vessels dilate and the blood flow increases. The dynamic vessel analysis (DVA) is a non‐invasive method to measure these processes. The DVA is often conducted under reduced ambient lighting conditions and biased by different adaptation levels, is used in repetitive tests with varying resting periods or is influence by different flicker contrasts. However the question of the impact of this technical and biological factors on the DVA is still not sufficiently clarified. This presentation will provide a brief introduction to the method of different experiment designs that can help to clarify these question. Finally, it will present current studies quantifying the influence of the factors.