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Cultivated Oral Mucosal Epithelial Transplantation
Author(s) -
Gatzioufas Zisis
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2019.8049
Subject(s) - transplantation , comet , medicine , stem cell , presentation (obstetrics) , disease , pathology , surgery , biology , astrobiology , microbiology and biotechnology
Bilateral limbal stem cell deficiency (BLSCD) represents a highly demanding challenge for the clinician dealing with ocular surface disease, due to the underlying causes, clinical presentation, as well as lack of a source of autologous limbal stem cells. Cultivated Oral Mucosal Epithelial Transplantation (COMET) has been successfully employed to achieve visual rehabilitation in patients with BLSCD. This talk will focus on indications, technique, clinical results and complications of COMET. Moreover, it will present current disadvantages and limitations of COMET, exploring potential advancements in the future.