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Affection of neuroretina and ocular motility in patients affected by Thalidomide Embryopathy
Author(s) -
PérezVelilla Javier,
Vicente María José,
Palomar Elisa Vilades,
Hospital Elvira Orduna,
Ciordia Beatriz Cordón,
Velilla Jose,
Rodrigo Maria Jesús,
Satué Maria,
GarcíaMartín Elena
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2019.5170
Subject(s) - nerve fiber layer , medicine , retinal , ophthalmology , visual acuity , thalidomide , multiple myeloma
Thalidomide embryopathy is a syndrome that associates abnormalities and congenital malformations as a result of intra‐uterine exposition to Thalidomide. The objective of this study is to evaluate the affection in neuro‐retina and ocular motility. Clinical cases We present 8 clinical cases that underwent the visual acuity measurement by ETDRS test, evaluation of tropia or phoria through the Cover Test, eye movements exam and macular and retinal fiber layer thicknesses by Triton SS‐OCT (Topcon Corporation, Japan). In half of the clinical cases, we observed low visual acuity and/or endophoria. Most of them have some decrease in retinal nerve fiber layer thickness. One of them has a restriction in eye movements. Conclusion There is retinal nerve fiber layer decrease and notable visual acuity reduction in patients with thalidomide embryopathy.

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