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Physiological changes in retinal layers thicknesses measured with swept source optical coherence tomograph
Author(s) -
Velilla Javier Pérez,
Vicente Maria José,
Palomar Elisa Viladés,
Hospital Elvira Orduna,
Palomar Amaya Pérez Del,
Banzo Jose Cegoñino,
Marco Alberto Montolio,
Palacián Maria Satué,
Martín Elena García,
Ciordia Beatriz Cordón
Publication year - 2019
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2019.5169
Subject(s) - retinal , retina , ophthalmology , choroid , optical coherence tomography , nerve fiber layer , quadrant (abdomen) , ganglion cell layer , ganglion , medicine , retinal ganglion cell , tomography , anatomy , biology , surgery , neuroscience , radiology
Purpose To evaluate the physiological changes of the different layers of the retina measured by the standard protocol and the grid points of the swept source optical coherence tomography (SS‐OCT). Methods A total of 463 eyes divided into four groups will be analyzed: Group 1 (71 eyes of subjects of 20 and 34 years); Group 2 (65 subjects from 35 to 49 years), Group 3 (with 230 subjects from 50 to 64 years) and Group 4 (97 subjects from 65 to 79 years). Wide protocol of Triton SS‐OCT (Topcon Corporation, Japan) was used to measure thickness of different layers of the retina, retinal nerve fiber layer (RNFL), ganglion cell layer, and choroid. Results Transition from group 2 to group 3 showed the most significant thinning of all the retinal layers, especially in the superior‐temporal quadrant of RNFL, ganglion cell and retinal layers (p < 0.001), and temporal sectors in the choroid layer (p < 0.001). A significant RNFL thickening was found in group 2 compared with group 1 in the superior temporal quadrant (p = 0.001), inferior half (p < 0.001) and temporal half (p = 0.001), and also in the choroid layer (p = 0.001). Conclusion There is a progressive and physiological thinning of all the layers of the retina from the third decade of life.