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Progressive changes in visual function after Descemet membrane endotelial keratoplasty
Author(s) -
Romero Sanz M.,
Gavín Sancho A.,
Satué Palacián M.,
Mateo Orobia A.,
Sánchez PérezBorbujo A.,
García Martín E.,
Blasco Martínez A.,
Idoipe Corta M.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.0s015
Subject(s) - photopic vision , scotopic vision , mesopic vision , medicine , ophthalmology , visual acuity , descemet membrane , contrast (vision) , glare , retinal , optics , chemistry , physics , organic chemistry , layer (electronics)
Purpose Objectives: To evaluate progressive changes in visual function parameters in patients with Fuchs endotelial dystrophy ( FED ) who underwent Descemet membrane endotelial keratoplasty ( DMEK ) and to compare visual results after DMEK with visual function parameters in healthy subjects without corneal pathology. Methods Methods: Fourteen patients (14 eyes) with FED who underwent DMEK surgery were included in the study. All subjects underwent best corrected visual acuity ( BCVA ) evaluation using the ETDRS optotype in photopic and scotopic conditions, and contrast sensitivity ( CS ) assessment using the CSV 1000 and the Pelli Robson tests in different lighting conditions, preoperatively, at 1 and 6 months after surgery. Fourteen eyes of 14 healthy controls were evaluated using the same protocol and compared with the patients’ final postsurgery data. Results Results: A significant improvement in all visual function parameters was observed in patients 1 month (p < 0.05) and 6 months (p < 0.05) after DMEK , compared with preoperative levels. Healthy controls had significantly higher BCVA in photopic and scotopic conditions (p = 0.02, p = 0.044, respectively), better CS in spatial frequencies of 6 cpd (p < 0.001); 12 cpd (p = 0.006) and 18 cpd (p = 0.006) measured with the CSV 1000 test, and CS as measured with the Pelli Robson test (p = 0.002). No significant differences were observed between patients and healthy controls in the spatial frequency of 3 cpd (photopic, p = 0.704; mesopic, p = 0.596; mesopic with glare, p = 0.989). Conclusions Conclusions: DMEK improves visual function parameters in patients with FED in the first month after surgery. Patients who underwent DMEK present similar CS to healthy subjects in lower frequencies. However, BCVA and CS in medium and high frequencies remain significantly lower than those values found in healthy corneas.