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Intravitreal bevacizumab administration for complicated retinal arterial macroaneurysm in a young male patient
Author(s) -
Popa Cherecheanu A.,
Pirvulescu R.,
Dide C.,
Iancu R.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.0f025
Subject(s) - medicine , bevacizumab , ophthalmology , retinal , visual acuity , asymptomatic , intravitreal administration , surgery , chemotherapy
Purpose Retinal arterial macro aneurysms ( RAM ) represent aquired retinal vascular disorders encountered predominantly in elderly, with marked female predominance, and most often associated with hypertension, arteriosclerosis and cardiovascular disease. In this poster we try to assess functional and anatomical results after bevacizumab (Avastin) injection in a young male with complicated RAM . Methods A 27 years old male presented in our clinic with decreased visual acuity into the right eye with the debut 10 days before. The patient underwent a comprehensive ophthalmologic and OCT examination. The diagnosis of retinal arterial macroaneurysm complicated with macular edema associated with lipoprotein exsudation was established. The patient underwent intravitreal injection of bevacizumab (Avastin) 1.25 mg/0.05 ml; two follow‐up visits were planned at 1 and 4 weeks after bevacizumab intravitreal administration. Results At 4 weeks after intravitreal bevacizumab, right eye BCVA improved from 0.17 log MAR to 0.1 log MAR ; the retinal hemorrhage reduced considerable, retinophotography demonstrated resolution of the exsudative changes and OCT examination showed physiologic appearance of the fovea. The patient underwent thorough investigations in cardiovascular area, including cerebral MRI . He was also proposed for retinal angiofluorography. Conclusions Although many patients are asymptomatic, decreased visual acuity is the most frequent symptom, and it is determined by hemorrhage and/or macular edema with macular star formation. The differential diagnosis of RAM includes retinal and systemic diseases that require thorough investigation.