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Irradiation induced optic neuropathy
Author(s) -
Zografos L.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.03544
Subject(s) - medicine , optic neuropathy , ophthalmology , ischemic optic neuropathy , complication , ischemia , retinal , visual acuity , central retinal vein , anterior ischemic optic neuropathy , conservative management , optic nerve , panretinal photocoagulation , surgery , diabetes mellitus , diabetic retinopathy , endocrinology
Summary Irradiation induced optic neuropathy is a major complication of conservative management of intra‐ocular tumors. An irradiation dose of 20 Gy or more delivered on the optic disk is the major risk factor. The final visual acuity in case of irradiation induced optic neuropathy is 0.2 or more only in 25% of the cases. Vascular damage can be located in the retrobulbar arteriovenous network, on the choroidal peripapillary network and on the central retinal artery or vein. In case of retinal ischemia, panretinal photocoagulation and intravitreal anti‐ VEGF medication is currently used. The preventive use of anti‐ VEGF and steroids is still controversal.