Molecular diagnostics of ocular allergy

Summary Ocular allergies may severely impact on daily activities and overall quality of life. Conventional allergy testing with skin prick tests and circulating serum immunoglobulin E often falls short of identifying the culprit ocular allergens. On the other hand, targeting the ocular milieu may prove valuable for ocular allergy diagnostics. Conjunctival provocation testing and specific immunoglobulin E detection in tear fluid provide data on local ocular hypersensitivity. We focused on specific IgE testing by means of a commercial allergen microarray ( ISAC ® 112, Thermo Fisher Scientific). We report here the contribution of allergen microarray testing to identifying the culprit allergen in a 42‐year old woman presenting with perennial allergic conjunctivitis.