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OCT and retinal ganglion cell layer
Author(s) -
Borruat F.X.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.03134
Subject(s) - retinal ganglion cell , neuroscience , neuroprotection , retinal , ophthalmology , medicine , retina , biology
Summary Vision is highly dependent on both retinal ganglion cells ( RGC ) and their axons. Vision salvation depends on the prevention of RGC loss, and the time window to initiate a neuroprotective therapy after injury is not well defined in humans. Recent developments in both OCT technology and software have allowed a precise and reproducible assessment of the RGC layer to be possible in vivo in humans. The goals of this presentation are two‐fold : first, to review the mechanisms of both axonal and RGC degeneration; second, to discuss the time‐course of RGC loss after either antechiasmal or retrogeniculate lesions. At the end of the talk, participants should understand the mechanisms and time‐course of RGC and axonal loss.