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Aqueous humor cytokines report in congenital cataract
Author(s) -
SAUER A.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.02664
Subject(s) - medicine , cataracts , cataract surgery , senile cataract , glaucoma , uveitis , ophthalmology , pathogenesis , inflammation , presentation (obstetrics) , congenital glaucoma , aqueous humor , surgery , pathology , immunology
Summary Congenital cataract and glaucoma are an important cause of lifelong visual impairment. The management of these diseases is specific because of physiological and anatomical features of the children eye and changes related to growth. Compared to the management in adults, the strong inflammatory tissue reactivity following surgery is particularly noteworthy and challenging in post‐operative care. The presence of postoperative fibrinous uveitis is thus not uncommon in children, notably after cataract surgery. Many intraoperative and post‐ operativetherapeutic options have been considered to minimize post‐operative inflammation, but none of these is formally recommended. The occurrence of post‐operative complications should be analysed in regard to intraocular inflammation. The aim of the presentation is to describe cohorts of congenital cataracts and glaucomas, to measure cytokines levels in operated eyes and to compare these levels to control groups (senile cataract). These datas will be discussed taking into account clinical determinants and previously published studies. These analyses may open new axes for the understanding of the pathogenesis of congenital cataract and glaucoma, based on inflammatory processes.