Uveal melanoma: millimeters, personalized prognosis, and new therapies

Summary The management of uveal melanoma is going through tremendous transition into the realm of early detection, personalized prognostication and potentially new systemic and local therapies. In this Keynote Lecture, we will discuss four topics relevant to current melanoma management including (1) the importance of detection of small melanoma where thickness is approximately 3 mm or less, (2) optical coherence tomography angiography ( OCTA ) of melanoma before and after plaque radiotherapy, (3) DNA analysis of >1000 cases of uveal melanoma and the ability to personally prognosticate each patient based on cytogenetic profile, and (4) new systemic and local therapies.