Premium
Vision improvement in dry and wet Age‐Related Macular Degeneration ( AMD ) patients after treatment with new corneal CPV procedure for light redirections onto the retina
Author(s) -
Serdarevic O.,
Tasindi E.,
Dekaris I.,
Berry M.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.01182
Subject(s) - macular degeneration , ophthalmology , medicine , retinal
Purpose To evaluate in two clinics vision improvement in AMD patients treated with a new corneal elastic modulus‐altering procedure ( CPV ) for light redirections onto multiple retinal areas. Methods Ten eyes (6 wet, 4 dry), with best‐corrected near and distance visual acuities ( CNVA and CDVA ) between 20/80 and 20/400, without pathological retinal morphology completely affecting the central 10° (3 mm) on OCT , were given a single treatment of CPV and were examined for 12 months post‐ CPV . Results Log MAR Mean CNVA and CDVA in treated eyes improved (p < 0.01) from pre‐ CPV 0.957 and 0.942 to 0.512 and 0.638, 0.544 and 0.602, 0.531 and 0.672 at 1, 6 and 12 m, respectively. The number of ETDRS letters gained in mean binocular CNVA / CDVA were 22/15, 25/19, 25/18 at 1, 6, and 12 m, respectively. Administered NEI VFQ ‐25 at 3 m improved from pre‐ CPV . No CPV complications or adverse events occurred. Conclusions CPV effectively, safely, rapidly and comfortably redirects light onto functional retinal areas after a single treatment to provide, without visual training, significantly improved monocular and binocular near and distance vision without causing peripheral field restriction or diplopia in patients with atrophic or neovascular AMD with poor vision, including after anti‐ VEGF therapy to which CPV is complementary and for which CPV may improve compliance because of improved vision restoration.