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Static vessel parameters in health and disease
Author(s) -
Heitmar R.
Publication year - 2017
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2017.01144
Subject(s) - retinal , disease , tortuosity , retina , medicine , ophthalmology , pathology , biology , neuroscience , engineering , geotechnical engineering , porosity
Summary Non‐invasive observation of the retinal circulation in vivo has seen more and more interest in clinical applications in recent years, not only because of ease of acquisition but also due to improved analysis software. Standardized semi‐automatic analysis of vessel calibers are useful markers in systemic vascular disease and have been shown to be linked with disease progression and future cardiovascular events. In recent years new vessel segmentation algorythms and analysis software has made it possible to assess not only vessel calibers but also parameters such as tortuosity, vessel density and branching patterns. In summary these vessel parameters in conjunction with measurements of retinal metabolism, vessel dynamics and retinal structure allow us to gain a better insight into normal retinal physiology and retinal pathophysiology due to systemic vascular disease.