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Retinal nerve fiber layer measurements in multiple sclerosis patients using new Swetpt‐Source Optical coherence tomography Triton device
Author(s) -
Cipres Alastuey M.,
Vilades Palomar E.,
Garcia Martín E.,
Satué M.,
Rodrigo M.J.,
Obis Alfaro J.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2016.0586
Subject(s) - nerve fiber layer , retinal , optical coherence tomography , inner limiting membrane , ophthalmology , ganglion cell layer , inner nuclear layer , nerve fibre layer , medicine , retina , multiple sclerosis , materials science , biomedical engineering , optics , physics , psychiatry
Purpose To evaluate retinal nerve fiber layer (RNFL) thickness measurements changes in multiple sclerosis (MS) patients using Swept‐source optical coherence tomography (SS‐OCT) Methods 101 healthy and 97 MS eyes were included. All of them underwent retinal evaluation using DRI Triton 3DH wide scan and retinal peripapillary thickness was analyzed: Total retinal thickness, CFNR, GCL+ (ganglion cells layer between CFNR and inner nuclear layer) and GCL++ (from the inner limiting membrane to inner nuclear layer) thickness were evaluated. Comparisons between the two groups were performed using Student's T test Results GCL+ showed significant thinning in MS patients compared to controls, in temporal, nasal and superonasal sectors; GCL++ and RNFL thickness were significantly lower in the MS group in all the sectors except nasal; total retinal thickness was lower in MS patients in all sectors. (p < 0.05) Conclusions Peripapillary retinal structural alterations can be detected in MS patients using SS‐OCT Triton. Further studies comparing Spectral domain and Swept source OCT are needed to demostrate superior capability of SS‐OCT technology to detect retinal changes in these patients.