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Integrated visual field and relative risk for quality of life loss
Author(s) -
Munoz M.,
Pujol O.,
Mora C.,
Pastor L.,
Gudiña S.,
Maull R.,
Vega Z.,
Morilla A.,
Anton A.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2016.0332
Subject(s) - medicine , quality of life (healthcare) , relative risk , visual field , ophthalmology , confidence interval , nursing
Purpose To assess cut‐point values of the integrated visual field (IVF), and their relative risk, associated with a higher risk for quality of life (QoL) loss. Methods 489 subjects were included. 51healthy and 438 glaucoma patients. IVF was calculated from monocular visual field, best location method. IVF score (IVFS) was calculated (Crabb). IVF was divided into six zones. All subjects completed three different questionnaires. Global quality of life was evaluated with EuroQol‐5D (EQ‐5D). Vision related quality of life was assessed with Visual Function Questionnaire (VFQ‐25) and with ocular surface disease Index (OSDI). ROC curves were built and cut‐point for best sensitivity and specificity values were calculated. Relative risk for suffering bad QoL was also assessed for each dimension with a ROC area >0.6. Results IVFS ≥ 3 was associated with a worse QoL related to general vision with a relative risk (RR) of 3.19. IVFS ≥ 5.5 was associated with a worse QoL related to color vision and mental health with a RR of 2.79 and 1.91, respectively. IVFS ≥ 6.5 was related to worse QoL related to dependency with a RR of 2.40. IVFS ≥ 9.5 was associated with a worse QoL related to ocular surface disease with a RR of 2.86. IVFS ≥ 10.5, 12.4 and 14.5 were associated with a worse QoL related to general vision, distance activities and peripheral vision, respectively, with a RR of 3.19, 3.30 and 2.86, respectively. All these RR had p < 0.05. IVF was divided into six zones, and OSDI and the same dimensions of VFQ‐25 presented the ROC areas > 0.6. Risk for loss in QoL was related to a mininum decrease in IVF in central zones and required greater loss in the peripheral zones. Conclusions Higher values of IVFS and small deficits in central IVF are associated to two or three folds risk of having loss of QoL in glaucoma patients.