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Factors influencing intravitreal Bevacizumaband triamcinolone treatment in patients with diabetic macular edema
Author(s) -
Lee M.Y.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2016.0244
Subject(s) - medicine , macular edema , diabetic macular edema , acetonide , ophthalmology , triamcinolone acetonide , edema , dexamethasone , retinal , optical coherence tomography , diabetic retinopathy , surgery , diabetes mellitus , endocrinology
Purpose To evaluate factors associated with the response of intravitrealbevacizumab (IVB) and intratreal triamcinolone acetonide (IVTA) in diabetic macular edema (DME) Methods 71 eyes of 55 patients with DME were incorporated in this retrospective study. Group 1 included eyes showed good response to IVB. Group 2 included eyes which did not respond to IVB but responded to IVTA. Group 3 included eye which did not respond to both. Clinical factors, HbA1c and optical coherence tomography (OCT) findings including patterns of macular edema were compared among three groups Results 44, 27, 20 eyes were included in group 1, 2, and 3, respectively. HBA1c was higher in group 3 than other groups. Proportion of full (combination of all patterns) type edema were higher in group 3 than the other two groups. In group 1, proportion of sponge‐like diffuse retinal thickening type was higher and cystoid macular edema type was lower than the other groups. Conclusions The degree of diabetic control and morphologic subtypes with OCT should be considered to better predict the prognosis after treatment in DME.