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Controversies between retinal dystrophies and uveitis – the point of view of the uveitis specialist: does retinal antibody detection help?
Author(s) -
Willermain F.,
Draganova D.,
Leroy B.P.,
Caspers L.,
Postelmans L.,
Corazza F.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2016.0130
Subject(s) - retinal , medicine , uveitis , ophthalmology , retinopathy , antibody , immunology , diabetes mellitus , endocrinology
Summary Many diseases, presumed to be mediated by autoimmune mechanisms, may have clinical picture suggestive of retinal dystrophies. The paradigm of such cases is illustrated by cancer associated retinopathies. However the spectrum of antibody mediated retinopathy is expanding and non neoplastic forms are grouped under the name autoimmune retinopathy (AIR). However, the difficulties to demonstrate the presence of retinal antibodies, as well as their presence in control and retinal dystrophy patients render the diagnosis very challenging. In this talk, we will, through case reports, illustrate the potential usefulness and pitfalls of antiretinal antibody search in the management of such cases.