Premium
OCT‐A and FA in irradiation induced microangiopathy
Author(s) -
Zografos L.
Publication year - 2016
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2016.0059
Subject(s) - medicine , brachytherapy , microangiopathy , angiography , plexus , radiation therapy , maculopathy , irradiation , complication , ophthalmology , radiology , surgery , retinopathy , diabetes mellitus , physics , nuclear physics , endocrinology
Summary Irradiation induced microangiopathy of the macular area is a severe complication of conservative management of uveal melanomas with with proton beam teletherapy or plaque brachytherapy. It occurs in 20–30% of the cases according the position of the posterior margin of the tumor and the selection criteria for the various therapeutic options. The aim of this study is to present the anatomic damage observed in fluoresceine angiography and OCT‐angiography as well as the modifications observed in B‐mode OCT and OCT en face. Following the evaluation of 80 cases of irradiation induced maculopathy, the most meaningfull anatomic damage, which correlates with visual function are the modifications of the outer perifoveal capillary plexus. According the results of this study, a therapeutic approach with anti‐VEGF's can be considered in all the cases presenting minimal or mild vascular damage.