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Efficacy of Dry Eye Disease Treatment based on the 2007 Report of the International Dry Eye WorkShop ( DEWS )
Author(s) -
Utheim O.,
Ræder S.,
Utheim T.P.,
Eidet J.R.,
Badian R.,
Stojanovic A.,
Chen X.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0685
Subject(s) - medicine , meibomian gland , ophthalmology , eyelid
Purpose To assess the effect of dry eye disease ( DED ) treatment according to the guidelines reported by the International Dry Eye WorkShop ( DEWS ) in 2007. Methods Dry eye disease patients with or without meibomian gland dysfunction ( MGD ), treated at the Norwegian Dry Eye Clinic, with at least 6 months follow‐up time were consecutively included in the study. The choice of treatment for DED was based on the dry eye severity level ( DESL ), according to the 2007 Report of the International Dry Eye WorkShop ( DEWS ). The values of tear film break‐up time ( TBUT ), Schirmer I test, ocular surface staining (Oxford scale), and dry eye severity level ( DESL ) on the right eye at 1, 3, 6, 12, and 24 months after the treatment were compared with those prior to treatment. Results A total of 237 eyes were included. At 6 months follow‐up, TBUT increased from 5.07 ± 3.63 s to 8.54 ± 5.12 s (p < 0.001); Schirmer I test did not show significant change; ocular surface staining decreased from 1.64 ± 2.13 to 0.76 ± 1.20; and DESL decreased from 2.08 ± 0.47 to 1.72 ± 0.54 (p < 0.001). The improvement of TBUT , ocular surface staining, and DESL remained significant at 24 months follow‐up. Conclusions Treatment based on the 2007 Report of the International Dry Eye WorkShop ( DEWS ) was effective in a Norwegian cohort of DED patients with significant improvement in key parameters for assessing DED .