Premium
Focal choroidal changes on diabetic macular edema
Author(s) -
Duarte L.,
Ruão M.,
Gallego R.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0614
Subject(s) - medicine , diabetic retinopathy , ophthalmology , macular edema , edema , diabetes mellitus , retinal , retinopathy , diabetic macular edema , stage (stratigraphy) , surgery , endocrinology , paleontology , biology
Purpose With the increasing interest in choroidal changes in Diabetes, we performed a pilot and prospective study to evaluate the morphological choroidal findings in diabetic macular edema detected with SD ‐ OCT , compared with normal or non‐macular edema diabetic eyes. Methods Two groups of patient were selected: Diabetic patients with no or any stage of diabetic retinopathy with no history of ocular treatment; and non‐diabetic patients as normal controls. Patients with other ocular diseases or surgery where not included. Complete ophthalmological exam was performed. A retinography, blood pressure measurement and OCT with the EDI or choroidal acquisition protocol was performed to all patients. For the analysis choroidal thickness was measured using automated calculation after manual segmentation. OCT images were analyzed for morphological changes in the choroidal space and vasculature, and findings were recorded. Results 47 eyes were included in this study: 11 with macular edema, 16 with non‐proliferative diabetic retinopathy, 10 from diabetic patients with no retinopathy and 10 control. Age ranged from 41 to 80 and matched for the sub‐groups. Choroidal thickness varied from 75 µm to 383 µm and no correlation was found with age, blood pressure or diabetic stage, except for advanced stages of retinopathy and macular edema where it appears to have a change in the architecture of the choroidal vessels with a tendency of vanishing of the large vessels in favor to the choriocapillaris, well related to the subjacent area of retinal active disease and edema. Conclusions As a pilot study, the results only can direct to larger sample studies in order to look for the meaning of choroidal changes that are being reported in diabetic patients and other ocular diseases. It suggests that thickness changes may be due to specific vascular changes.