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Changes in choroidal thickness after intraocular pressure reduction following trabeculectomy
Author(s) -
Kadziauskiene A.,
Kuoliene K.,
Galgauskas S.,
Asoklis R.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0586
Subject(s) - medicine , trabeculectomy , choroid , ophthalmology , intraocular pressure , glaucoma , optic nerve , thickening , optical coherence tomography , retina , chemistry , physics , polymer science , optics
Purpose To evaluate changes of choroidal thickness (CT) after an acute reduction in intraocular pressure (IOP) following trabeculectomy. Methods Subfoveal and peripapillary CT and IOP were measured in 40 glaucomatous eyes (40 patients) 1 day before, 1 week and 1 month after the trabeculectomy. The choroid was evaluated using spectral domain optical coherence tomography enhanced depth imaging at the fovea and 1.7 mm superior, temporal, inferior and nasal to a optic nerve head centre. Biometry was performed preoperatively. Results The mean IOP was significantly reduced after trabeculectomy at both follow‐up visits ( P < 0.001). The mean subfoveal CT (±SD) increased from 216.1 (±86.1) µm at baseline to 260.3 (±86.9) µm after one week and 243.1 (±87.1) µm after one month postoperatively ( P < 0.001). The mean CT significantly increased one week after trabeculectomy at all peripapillary locations ( P < 0.01), however, the thickening of choroid was significant only temporally after one month. There was positive correlation between the magnitude of change in subfoveal CT and the IOP reduction ( r = 0.518 , P < 0.001 for the 1‐week follow‐up ; r = 0.290 , P = 0.034 for the 1‐ month follow‐up). The preoperative axial length correlated positively with the magnitude of thickening of subfoveal CT after one week ( r = 0.451, P = 0.002). Conclusions The subfoveal and peripapillary CT increased with the IOP reduction following trabeculectomy, however, choroidal thickening around the optic nerve disc appeared to be short‐term. The thickening of subfoveal CT was found to be related to the greater IOP reduction and longer axial length.