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Correlation of hyperreflective foci, status of photoreceptor layer, and visual acuity in diabetic macular edema
Author(s) -
Chebil A.,
Ben Abdallah M.,
Kort F.,
Hassairi A.,
Maamouri R.,
El Matri L.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0463
Subject(s) - ophthalmology , medicine , retinal , visual acuity , optical coherence tomography , retina , external limiting membrane , diabetic macular edema , outer nuclear layer , macular edema , edema , diabetic retinopathy , retinal pigment epithelium , diabetes mellitus , surgery , optics , physics , endocrinology
Purpose To investigate the correlation ofhyperreflective foci, photoreceptor integrity and visual acuity ( VA ) in patients with diabetic macular edema ( DME ). Methods Seventy‐eight patients (114 eyes) with DME were analyzed retrospectively with Spectral‐domain optical coherence tomography ( SD ‐ OCT ). Results SD ‐ OCT showed that 28 eyes (24.5%) had hyperreflective foci in the inner retinal layers, and 66 eyes (57.9%) had hyperreflective foci in the outer retinal layers. The log MAR VA was significantly (P < .0001) worse in eyes with hyperreflective foci in the outer retinal layers than in eyes without them (0.478 ± 0.241 vs 0.133 ± 0.233, respectively). Disruption of the ellipsoid zone and ELM line on OCT were significantly (respectively P < .0001 and P < .0001) associated with both hyperreflective foci in the outer retinal layers and poor log MAR VA . Conclusions The presence of hyperreflective foci in the outer retina is closely associated with a disrupted ELM and ellipsoid zone on SD ‐ OCT images and decreased VA in DME .