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Correlation of Osmolarity Measurements with Signs and Symptoms in the Norwegian Dry Eye Clinic
Author(s) -
Badian R.A.,
Eidet J.R.,
Ræder S.,
Utheim Ø.,
Chen X.,
Stojanovic A.,
Utheim T.P.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0422
Subject(s) - medicine , ophthalmology , norwegian , osmotic concentration , cohort , philosophy , linguistics
Purpose To evaluate the relationship between osmolarity and signs and symptoms of dry eye disease ( DED ) in a Norwegian cohort of patients with DED . Methods Clinical signs and symptoms were evaluated for 365 subjects at the Norwegian Dry Eye Clinic. All patients received an extensive ophthalmological work‐up, including tear meniscus height, blink rate, corneal sensibility, tear film break‐up time, Ocular Protection Index, vital staining, Schirmer I, meibum quality and meibum expressibility. Pearson correlations between signs and symptoms were performed. P values below 0.05 were considered significant. Results High osmolarity correlated with lower ocular protection index (0.32) and higher blink interval (0.12), but no other parameters. Conclusions Osmolarity did not correlate strongly with any parameters of dry eye disease.