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The effect of panretinal photocoagulation and additive Intravitreal bevacizumab injections on central retinal vessel diameters in diabetic retinopathy
Author(s) -
Park J.M.,
Lee S.J.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0412
Subject(s) - panretinal photocoagulation , medicine , diabetic retinopathy , retinal , ophthalmology , bevacizumab , central retinal vein , central retinal artery , diabetes mellitus , surgery , chemotherapy , endocrinology
Purpose To evaluate the effect of Panretinal photocoagulation and additive Intravitreal bevacizumab injections on Central retinal vessel diameters in Diabetic retinopathy. Methods Changes on central retinal vessel diameters were restrospectively analyzed before and 6 month after panretinal photocoagulation with or without additive Intravitreal bevacizumab injections in patients first diagnosed with diabetic retinopathy. Vessel diameters were measured using IVAN soft ware and Big6 fornula. Results 21 patients were enrolled, mean age 54.9 years. There were significant decreases in central retinal artery diameters in both groups, with and without additive Intravitreal bevacizumab injections, 6 months after completion of panretinal photocoagulation(p < 0.05), but no significant changes in central retinal vein diameters. Additive Intravitreal bevacizumab injections did not bring the significant changes in central retinal vessel diameters before and after 6 months, compared to vessel diameters treated with panretinal photocoagulation only (p < 0.05). Conclusions Panretinal photocoagulation has effects on changes of central retinal artery diameters but not central retinal vein diameters, and additive Intravitreal bevacizumab injections did not cause significant additive changes on central retinal vessels in this study. meters before and after 6 months, compared to vessel diameters treated with panretinal photocoagulation only(p < 0.05).