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Update on lymphoma diagnostic
Author(s) -
Coupland S.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0232
Subject(s) - lymphoma , nodular sclerosis , pathology , neoplasm , medicine , hodgkin lymphoma , lymphocyte , disease , immunology
Summary Lymphomas are classified according to the current WHO classification, which emphasizes an approach whereby the clinical characteristics are correlated with distinct morphological, immunophenotypical, and genotypical features of each neoplasm. The classification of lymphoid malignancies recognizes three major categories: B‐cell neoplasms, T‐/ NK ‐cell neoplasms, and Hodgkin lymphomas. B‐ and T‐cell lymphomas are further classified into precursor‐ and mature neoplasms, the latter being subdivided again according to their clinical manifestation: i.e. into disseminated/leukemic, extranodal and nodal malignancies. Hodgkin's disease, now more appropriately termed Hodgkin lymphoma, comprises nodular lymphocyte‐predominant Hodgkin lymphoma and classical Hodgkin lymphomas of nodular sclerosis, mixed cellularity, lymphocyte‐depleted and lymphocyte‐rich subtype. This talk will provide a summary of the major lymphoid malignancies affecting the eye, and an overview of the techniques used to diagnose them.