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Stromal choroiditis in East ( VKH ) and West (birdshot)
Author(s) -
Herbort C.P.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0093
Subject(s) - choroiditis , medicine , vogt–koyanagi–harada disease , fundus (uterus) , ophthalmology , indocyanine green angiography , fluorescein angiography , dermatology , retinal , uveitis
Summary Background and aim Both Vogt‐Koyanagi‐Harada ( VKH ) disease and birdshot retinochoroiditis ( BRC ) are primary stromal choroiditis entities, meaning that the initial inflammatory process necessarily starts in the choroidal stroma. The aim here was to point out similarities and differences between these two stromal choroiditis entities and to show that early treatment is able to modify the phenotypes of both conditions. Patients and methods Two groups of patients respectively of VKH and BRC cases were analyzed and followed clinically and angiographically using dual fluorescein ( FA ) and indocyanine green ( ICGA ) angiography.Results: 13 of 28 BRC patients and 11 of 24 VKH patients had enough follow‐up data to be included in the study. Early diagnosis and treatment in both VKH (9/11) and BRC (6/13), allowed to avoid sunset glow fundus in the former and BRC fundus lesions in the latter. The main similarities and differenced will be pointed out. Conclusion VKH and BRC differ substantially from each other. However choroidal stromal inflammation is characterized by a similar process and responds equally to therapy.