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En face OCT
Author(s) -
Scemama Timsit C.,
MaugetFaÿsse M.,
Wolff B.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0075
Subject(s) - retinal , retina , retinitis pigmentosa , atrophy , medicine , ophthalmology , retinal degeneration , macular degeneration , outer nuclear layer , stargardt disease , nerve fiber layer , macular dystrophy , pathology , anatomy , biology , neuroscience
Summary “En face” OCT (Spectral Domain and Swept Source) realizes frontal section of the retina or C‐scans. “En face” OCT software informs immediately the layer of the cuts; it joins viewing images “en face” and B‐scan with the graphical representation of their different scans. Normal retinal layers have their specific reflectivity. Atrophy can occur at different stages of many retinal diseases, and at different retinal layers. On “en face” OCT , there are 2 main areas to consider in case of atrophy in retinal diseases: ‐ the inner nuclear layer which may presents pseudocystic lesions that reflect a damage inducing optic nerve atrophy, ‐ the outer retinal layers in degenerative retinal diseases such as age related macular degeneration ( AMD ), genetic diseases such as Stargardt's macular dystrophy, retinitis pigmentosa, MacTel type 2 and in inflammatory diseases such as Serpiginous and Birdshot retino choroidopathies. The pseudocystic lesions might represent a mitochondrial dysfunction inducing degeneration of Muller cells. The outer retinal damage can be related to material resorption (drusen, pseudodrusen, PED ), disappearance of choriocapillaris, ellipsoid disruptions .”En face” has increased the understanding of atrophy in retinal disease.