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The RPE /photoreceptor complex
Author(s) -
Osborne N.
Publication year - 2015
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2015.0055
Subject(s) - retinal pigment epithelium , choroid , bruch's membrane , microbiology and biotechnology , epithelium , retina , photoreceptor cell , anatomy , biology , chemistry , neuroscience , genetics
Summary The retinal pigment epithelium ( RPE )/ photoreceptor complex constitutes the choroid, bruch's membrane and the photoreceptor outer segments. The RPE interacts with bruch's membrane and the photoreceptors, which it faces across the subretinal space. In these interactions the RPE acts as three types of cell ‐ epithelium, macrophage, and glia. There are a number of selective interactions between the choroid, bruch's membrane, RPE and photoreceptors related to ion and water transport, vitamin A transport, phagocytosis of shed portions of outer segments, ensheathment of photoreceptors outer segments, and electrical responses. One purpose of the course is to discuss the RPE /photoreceptor complex in terms of structure and function.