ANGIO ‐ OCT and DMLA (diagnosis and post‐treatment follow‐up)

Summary To compare the OCT Angiography ( OCT ‐A) findings to the traditional multimodal imaging ( TMI ) in patients with exudative AMD ( eAMD ) in terms of diagnosis and treatment decision. 80 eyes of 73 consecutive eAMD patients diagnosed with different types of CNV were enrolled. The data obtained from the TMI , based on Fluorescein Angiography ( FA ), Indocyanine green angiography ( ICGA ) and OCT , were compared with the ones achieved by OCT ‐A (Spectralis, Heidelberg Engineering, Heidelberg, Germany). The lesion's activity in TMI was established according to leakage on FA , evidence of CNV network on ICGA and fluid accumulation on OCT , while in OCT ‐A was based on the shape, the branching pattern, the anastomoses, the vessel termini and the perilesional hypo‐intense halo. Both OCT ‐A and TMI allowed the recognition of 5 types of neovascularization (Type I, Type II , Mixed Type I‐ II , CRA , AMD ‐related polyps). The two methods achieved the same diagnosis in 95% of cases. The percentage of full agreement in determining the CNV activity between the two imaging protocols was 92.5%. Our study highlights the capability of OCT ‐A to diagnose, determine the type, grade the activity and guide the treatment of a choroidal neovascular lesion in an eAMD patient.