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The application of Colour Contrast Sensitivity test to the early prediction of chiasm damage in cases of pituitary adenoma
Author(s) -
KRIAUCIUNIENE L,
SLATKEVICIENE G,
LIUTKEVICIENE R,
ZALIUNIENE D,
BERNOTAS G,
GLEBAUSKIENE B,
TAMASAUSKAS A
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.t102.x
Subject(s) - medicine , optic chiasma , optic chiasm , ophthalmology , fundus (uterus) , pituitary adenoma , contrast (vision) , audiology , adenoma , nuclear medicine , optic nerve , artificial intelligence , computer science
Purpose Our objective was to estimate the maximum colour contrast sensitivity (MCCS) thresholds in persons with damage of chiasma opticum. Methods Forty one persons with pituitary adenoma (PA) and 100 persons as age and gender matched controls were examined. Patients were divided into groups: according to who had chiasmal compression on imaging and who had not. A new computerized MCSS test program was used for colour discrimination. Results The mean of error score (ES) of MCCS in the group without chiasmal compression was 1.8 [SD, 0.38], in the group with chiasmal compression it was 3.5 [SD, 0.96], and in the control group it was 1.4 [SD, 0.31], (P<0.001). When visual acuity and visual field and fundus were normal in patients with PA, MCCS ES were 3.3 [SD, 1.8], and when VA was less than 1.0 the results were – 4.6 [SD, 2.9]. Conclusion Results of MCSS test ES were 1.9 times better in patients who had not chiasmal compression compared to patients who had chiasmal compression (P<0.001). Even when VA was normal in PA patients group, their ES was 2.35 times worse compared to healthy persons, P<0.001. Financial support: Lithuanian Science Council (grant no. MIP‐008/2014).