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Progression rate in glaucoma using spectral‐domain optical coherence tomography
Author(s) -
LEE Y
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.t032.x
Subject(s) - medicine , ophthalmology , optical coherence tomography , nerve fiber layer , retinal , glaucoma , visual field , quadrant (abdomen) , surgery
Purpose To evaluate the thining rates of retinal nerve fiber layer (RNFL), macular and ganclion cell‐inner plexiform layer (GC‐IPL) thickness in eyes with POAG, NTG and ACG. Methods Retrospective cohort study included 145 eyes of 90 glaucoma patient(POAG 70; NTG 60; ACG 15). RNFL, macular and GI‐IPL thickness were measured by spectral‐domain optical coherence tomography (Cirrus SD‐OCT). Also all the patient was re‐classified as 3 groups according to visual field severity (early, moderate and advanced) and as 3 groups according to spherical equivalent (myopia, mild myopia and hyperopia). The meaningful thining was defined on exceed the age‐related physiological loss. Results The mean (±SD) follow‐up period was 3.86±0.16 years. ACG eyes showed highest progression rate of RNFLT in all of quadrant and clock hour. NTG eyes showed no significant different in average RNFLT but significantly higher RNFL thining rates than POAG in inferior quadrant. In ACG eyes, RNFLT thining rate is highest in clock‐hour‐6. In NTG eyes showed highest in clock‐hour‐7 while similar rate in clock‐hour‐7 and clock‐hour‐12 in POAG eyes. Thining of macular thickness is highest at outer inferior sector and thining of GC‐IPL is highest in inferior sector and inferior hemifield. Thining rate of RNFLT is slower in myopic eyes than mild myopic and hyperopic eyes. In the advanced group, thining rate of RNFLT is slower than early and moderate groups. Conclusion Reduction rate of RNFL, macular and GC‐IPL thickness calculated by Ciruss SD‐OCT is differ according to the types of glaucoma, spherical equivalent and severity of glaucoma.