Premium
Changes of corneal endothelium in diabetes patients after cataract phacoemulsification surgery by confocal microscopy
Author(s) -
LIN J,
ZHAO G
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.s084.x
Subject(s) - phacoemulsification , corneal endothelium , medicine , ophthalmology , coefficient of variation , diabetes mellitus , cataract surgery , hexagonal crystal system , endothelium , intraocular lens , confocal microscopy , confocal , cornea , surgery , visual acuity , endocrinology , biology , chemistry , geometry , mathematics , chromatography , microbiology and biotechnology , crystallography
Purpose To observe the changes of corneal endothelium in diabetes patients before and after cataract phacoemulsification surgery with confocal microscopy for exploring the variation and influencing factors Methods Phacoemulsification were randomly divided into 50 aged related cataract patients with diabetes mellitus and 50 patients with senile cataract.Cataract phacoemulsification and intraocular lens implantation were performed central corneal thickness the corneal endothelial cell density coefficient of variation and percentage of hexagonal cell were measured before surgery 1 week 1 month and 3 months after surgery by confocal microscopy Results Before surgery there was no statistical difference between the two groups of central corneal thickness corneal endothelial cell density coefficient of variation and percentage of hexagonal cell Compared with pre operation the central corneal thickness and coefficient of variation were increased post operation but the corneal endothelial cell density and percentage of hexagonal cell decreased graduallyThe central corneal thickness of diabetes group was more significantly than control group 1 week 3 months after surgery, and the corneal endothelial cell density was less significantly than control groupOne week 3 months after surgery the percentage of hexagonal cell was less than control group. The coefficient of variation was significantly higher than control group. Conclusion Aged related cataract patients with diabetes mellitus were much more poor tolerability on cataract phacoemulsification surgery Compared with senile cataract patients the corneal endothelium injury was more serious and the velocity and validity of recovery were lower comparatively