Premium
In vivo and ex vivo confocal microscopy of eyelid melanoma: case report
Author(s) -
HAOUAS M,
GUILLEMOT C,
GRIVET D,
CINOTTI E,
PERROT JL,
LABEILLE B,
CAMBAZARD F,
FOREST F,
DUMOLLARD JM,
PEOC'H M,
GAIN P,
THURET G
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.s072.x
Subject(s) - eyelid , histopathological examination , medicine , ex vivo , melanoma , pathology , in vivo , confocal microscopy , confocal , radiology , biology , geometry , microbiology and biotechnology , mathematics , cancer research
Purpose We report the first description of a malignant melanoma (MM) of the eyelid margin examined by in vivo and ex vivo reflectance confocal microscopy (IVCM and EVCM). Methods A 65‐year‐old patient with a pigmented cutaneous tumor of the left upper eyelid margin was evaluated by clinical, dermoscopical and IVCM examination which suggested the diagnosis of MM. IVCM was performed with the handheld vivascope 3000 (Caliber/Mavig). Excision of the tumor with lateral margins of 2 mm was performed. Results The fresh excised tissue was examined by EVCM (vivascope 2500 ML) which found features of MM and showed that surgical margins were tumor‐free. The diagnosis of the MM was confirmed by the histopathological examination. Conclusion In addition to the clinical examination and dermoscopy, IVCM added evidence to the MM diagnosis and EVCM allowed to evaluate the excision margins before the histopathological examinations. Therefore IVCM and EVCM can provide to the clinician important elements to improve the diagnosis of MM and the management of the eyelid cutaneous melanocytic tumors.