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Ocular protection index is related to ocular surface disease index in dry eye disease patients
Author(s) -
BADIAN R,
UTHEIM TP,
RÆDER S,
UTHEIM Ø,
CHEN X,
STOJANOVIC A,
EIDET JR
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.s045.x
Subject(s) - medicine , medical prescription , disease , etiology , norwegian , cohort , ophthalmology , philosophy , linguistics , pharmacology
Purpose To assess symptoms and signs in a Norwegian cohort of dry eye disease (DED) patients by investigating the relationship between Ocular Protection Index (OPI) and Ocular Surface Index (OSDI). Methods DED patients of mixed etiologies were consecutively included in the study and defined as OPIhigh (OPI ≥ 1) or OPIlow (OPI < 1). All patients received an extensive ophthalmological work‐up. Groups were compared by using analysis of covariance (ANCOVA). Results Three hundred and twenty nine (329) DED patients were included. Seventy‐four of the 329 patients (22%) were OPIlow, whereas 255 were OPIhigh (68%). The two groups did not differ from each other with respect to either age (P= 0.063), gender (P=0.099) or in the number of systemic prescription drugs used (P= 0.586). After controlling for the effects of gender, age and the number of systemic prescription drugs used OPIlow patients had significantly higher OSDI scores (16.9±2.0) than OPIhigh patients (13.5±1.1) (P= 0,002). Conclusion A low OPI is related to a higher symptom load, as measured by the OSDI questionnaire.