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Intraocular Metastasis as presentation of unknown systemic neoplasia
Author(s) -
SAORNIL ALVAREZ M,
RAMOA R,
GARCIAALVAREZ C,
MUNOZ M,
LOPEZLARA F
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.4645.x
Subject(s) - medicine , enucleation , metastasis , presentation (obstetrics) , primary tumor , surgery , cancer
Purpose To assess the frequency of metastases as first presentation of systemic disease in a referral clinic, and to identify clinical characteristics. Methods Retrsopective study of consecutive csees diagnosed of intraocular metastasis at the referral intraocular tumors Unit. General and clinical characteristics were registered in a database design in Noraybanks (software approved by the research committe. Descriptive analysis was performed with SPSS 20.0. Results Between 1990 and 2013, 21 patients were diagnosed of intraocular metastasis with a mean age of 62.7 years (31‐89). Most frequent primary tumors were breast (47.6%) and lung (23.8%).Bilateral tumor was observed in 4 cases.The intraocular tumor was the first manifestation of the neoplasia in 13 cases (61.9%).Primary tumor was breast in 46.2% and lung in 38.5%, eshophagus in 7.7% and stomach in 7.7%.Reason for consultation was decreased vision in all cases. All 13 cases were unilateral and 75% as a solitary mass. Tumor was located at posterior pole in 69.2% and in all cases behind the equator.Diagnosis of primary tumor was performed by systemic studies and only one patient required intraocular biopsy. Ragrading the treatment, 7 cases were controlled with systemic chemotherapy, 4 cases required additional external beam radiotherapy and only one underwent to enucleation due to associated neovascular glaucoma Conclusion When intraocular metastases are the first presentation of unknown neoplasia used to be solitary non pigmented mass with retinal detachment.Early diagnosis is essential to settle prompt treatment to preserve visual function and improve the patient's prognosis.