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Amniotic membrane applications in children
Author(s) -
BREMONDGIGNAC D
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.2734.x
Subject(s) - medicine , neovascularization , ophthalmology , amnion , pregnancy , angiogenesis , biology , fetus , genetics
Amniotic membrane is the innermost, multilayered part of the placenta. Its properties, stemming from its biological composition, make it a useful tissue for ophthalmic surgery. It promotes epithelization, has antimicrobial effects, decreases inflammation, fibrosis and neovascularization. Reconstruction of conjunctival and corneal defects, treatment of corneal ulcers demonstrated the beneficial effect of amniotic membrane for different ophthalmological indications. The various properties and its current clinical use in ophthalmology are studied in children. Stem cell characteristics have a potential contribution to cell‐based treatment of ocular surface disease such as ocular burns and limbal deficiency. Some specific clinical cases are exposed and show the interest of the application of amniotic membranes in children.