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Doppler OCT
Author(s) -
WERKMEISTER R
Publication year - 2014
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2014.1612.x
Subject(s) - blood flow , doppler effect , fundus (uterus) , hemodynamics , biomedical engineering , microcirculation , optics , medicine , computer science , ophthalmology , radiology , physics , cardiology , astronomy
OCT is a non‐invasive imaging modality capable of providing information on sample structure with micrometer scale resolution. Doppler OCT (DOCT), a functional extension of OCT, provides knowledge about the motion of the sample and its substructures. It found its main application in biomedical imaging in the assessment of ocular blood flow. Doppler OCT allows for both measurement of blood flow velocities in larger retinal vessels and visualization of the vascular network. Recent developments such as dual beam DOCT make it possible to measure absolute blood flow velocity. Measurements are independent of the a priori unknown Doppler angle and further enable calculation of total blood flow when taking vessel diameter estimation via OCT or fundus camera based approaches into account. In addition, Doppler OCT allows for visualization of blood flow profiles and their alterations in retinal vessels and venous junctions and to further gain insight into hemodynamics as well as to study flow characteristics of the non‐Newtonian fluid blood. Results will be presented that show the potential of DOCT to provide crucial information for diagnosis, monitoring and treatment planning of ocular diseases related to alterations in ocular perfusion.