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Rare iridociliary pediatric tumors and pseudotumors: Cases report and literature review
Author(s) -
HADJISTILIANOU T,
TSYGANKOV A,
DE LUCA MC,
DEFRANCESCO SONIA,
MICHELI L,
BORRI M,
MENICACCI F
Publication year - 2013
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2013.s091.x
Subject(s) - juvenile xanthogranuloma , medicine , tuberculoma , retinoblastoma , differential diagnosis , ciliary body , iris (biosensor) , eye neoplasm , pathology , surgical pathology , radiology , dermatology , tuberculosis , histiocyte , biochemistry , chemistry , computer security , computer science , biometrics , gene
Purpose Iridociliary tumors are usually uncommon in childhood. Our aim is to describe cases of juvenile xanthogranuloma, iris tuberculoma and medulloepithelioma in young patients and to differentiate them from other similar lesions Methods Retrospective cases study. Four patients ( two girls and two boys) were referred at the Referral Center for Retinoblastoma of the University of Siena. They underwent all the ophthalmological examination including standard procedures, MRI of the orbits, CT, UBM, immunological and molecular analysis. In three cases organ‐preserving operations were performed. Results Two tumors were histologically identified as medulloepitheliomae. Two tumor‐like lesions were determined as juvenile xanthogranuloma and iris tuberculous granuloma. In the last case, antituberculous therapy was performed Conclusion Iridociliary tumors and pseudotumors are rather rare in childhood. Nevertheless, they should be taken in consideration in differential diagnosis with other pediatric intraocular tumors, particularly retinoblastoma, ciliary body adenoma and adenocarcinoma. An executive checkup including pathology, immunohistochemistry and immunology is to be performed.