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Adaptive optics imaging of retinal vasculitis
Author(s) -
ERRERA MH,
PAQUES M
Publication year - 2013
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2013.s064.x
Subject(s) - retinal vasculitis , vasculitis , medicine , fundus (uterus) , fluorescein angiography , retinal , pathology , lumen (anatomy) , ophthalmology , retina , disease , biology , surgery , neuroscience
Purpose To document perivascular infiltrates in the retina using high resolution flood illumination adaptive optics (AO) imaging in patients with retinal vasculitis. Methods The charts of five subjects with retinal vasculitis showing evidence of perivascular infiltrates by means of AO imaging (rtx1 camera, Imagine Eye, Orsay, France) were reviewed. Results Diagnoses included primary idiopathic retinal vasculitis (n=1), Lyme’s disease (n=2), TB related retinal vasculitis (n=1) and idiopathic retinitis, vasculitis and aneurysm (IRVAN; n=1). Using AO imaging, perivascular infiltrates appeared as discrete, linear areas of opacification along the veins, often surrounding the venous narrowing. AO imaging was more sensitive that either fundus photographs or fluorescein angiography for their detection. Follow‐up examinations (n=3) showed a changing pattern of narrowing of the vessel lumen, and eventual disappearance of these perivascular infiltrates. In the IRVAN case, inflammatory infiltrates were found around arterioles and veins as well, suggesting an inflammation induced‐phenomenon. Conclusion AO imaging has a higher sensitivity than fundus photographs or fluorescein angiography to detect perivascular inflammatory infiltrates. Vascular inflammation is strongly linked to changes in vascular lumen diameter. AO imaging may have a particular interest when diagnosis and following subjects with retinal vasculitis.