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IgG4‐Positive orbitopathy
Author(s) -
HEEGAARD S
Publication year - 2013
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2013.4646.x
Subject(s) - igg4 related disease , medicine , pathology , disease , lymphoid hyperplasia , orbit (dynamics) , incidence (geometry) , hyperplasia , biopsy , fibrosis , autoimmune pancreatitis , lymphoma , physics , optics , engineering , aerospace engineering
Purpose To give an overview of IgG4‐positive orbitopathy. A newly described disease of the orbit. Methods Critical review of the present literature demonstrated by a patient case. Results The clinical appearance, high incidence of bilateral disease, association with lesions in other organs, and increased IgG 4 serum levels along with the histological findings of IgG4–positive cells, more background fibrosis, lymphoid hyperplasia, plasma cells and eosinophils are the characteristics of this disease. Conclusion Patients with IgG4–positive cells in an orbital biopsy may have an orbital manifestation of IgG4‐associated systemic disease