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Irido‐ciliary tumours of the pigmented and non‐pigmented ciliary epithelium
Author(s) -
DAMATO B
Publication year - 2013
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2013.3244.x
Subject(s) - medicine , ciliary body , pathology , uvea , uveitis , iris (biosensor) , ophthalmology , eye disease , computer security , computer science , biometrics
Tumours of the pigmented and non‐pigmented ciliary epithelium include adenoma and adenocarcinoma, which can be pigmented or amelanotic according to whether they arise in the pigmented or the non‐pigmented ciliary epithelium. These tumours can invade the anterior chamber and corneal endothelium. They can be multinodular. Complications include pigment scatter, subluxation of the lens, cataract, vitreous seeding and haemorrhage. Necrosis can cause uveitis. Histological differentiation between adenoma and adenocarcinoma can be difficult. Malignant tumours can spread extraocularly to cause an epibulbar tumour or proptosis. Some tumours arise in blind, traumatized eyes. The differential diagnosis includes melanoma, melanocytoma, Fuch's adenoma, epibulbar squamous cell carcinoma and medullopithelioma. Diagnosis is best achieved by excision biopsy, which also provides a cure. Radiotherapy can be followed by persistent uveitis and glaucoma ('toxic tumour syndrome'). Treatment, if indicated, usually consists of excision, if possible conserving the eye with useful vision.