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Neuro‐ophtalmic complications of cancer chemotherapy
Author(s) -
KAWASAKI A
Publication year - 2013
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2013.2751.x
Subject(s) - medicine , etiology , complication , chemotherapy , radiation therapy , cancer , cranial nerve palsy , palsy , metastasis , surgery , pathology , alternative medicine
Cancer patients nowadays have longer periods of remission and higher rates of cure. The greater number of efficacious chemotherapeutics agents has no doubt contributed to prolonged survival rates for cancer patients but this has also led to a greater number of adverse and neurotoxic effects of chemotherapy. Sometimes, it is not easy to determine the exact etiology of a neuro‐ophthalmologic disorder as these patients have multiple potential causes : metastasis, nutritional or metabolic derangement, vasculopathy, paraneoplastic syndrome, complication of radiation. Nevertheless, it is important for the ophthalmologist to have some familiarity with the more commonly reported neuro‐ophthalmologic complications of chemotherpay. This lecture will discuss agents that have been associated with optic disc swelling, increased intracranial pressure, cranial nerve palsy and acute cerebellar syndrome.