Premium
AMD atrophic areas. Characteristics, evolution study, and its interest. 3 years follow‐up
Author(s) -
GONZALEZ C
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.s051.x
Subject(s) - atrophy , medicine , complication , incidence (geometry) , ophthalmology , surgery , pathology , mathematics , geometry
Purpose To evaluate the characteristics of AMD atrophic areas, their change, evolution and incidence or no of neovascular complication. Methods 134 eyes of 108 patients, 32 men, 76 women, with AMD Atrophic areas. Atrophic areas were evaluated by autofluorescence imaging Spectralis HRA +OCT (in particular with region finder software), OCT (notably choriocapillary depth), FA, ICG. We evaluate the size, characteristics, topography of the lesions, their growth way. The areas themselves, their edge and rim were considered and evaluated. Each element was studied, compared cut to cut and time to time to itself and to each other data, every 4 months. The impact of AMD and /or Neovascular complication on the evolution of atrophic areas is also valuate. Results VA impaired in 24% cases, stabilized in 76%. AF imaging and their region finder analyze were the main elements of the atrophic lesions’ study. The surface of the atrophic area grows by 14%, the edge changes in 20%, the rim increases 15% in 30% cases, with ZAC spared in 87%. Atrophy extension preferred nasal side, confluence in 65% when multiple areas. At OCT,thickness of photoreceptor, pigment epithelium layer diminished at area and edge. Choriocapillary depth values, FA and ICG data were mainly significative in the large atrophic areas and less than AF indications. Neovascular complication has few effects on atrophic areas evolution. Conclusion The study of atrophic process and its progression is a main question in AMD, its follow –up, its evolution, its increase. It also allows the evaluation of Neovascular complication impact. Atrophic areas are of main importance to AMD, either no or neovascular.