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Effects of Irifrin 2,5% on the disturbances pupillary‐accommodative system in patients
Author(s) -
BUSHUYEVA N,
MALIEVA O
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.f118.x
Subject(s) - medicine , accommodation , ophthalmology , pupillary response , visual acuity , pupil , balance (ability) , visual disturbance , optometry , surgery , psychology , physical therapy , neuroscience
Purpose The disturbances of pupillary‐accommodative system in раtients include astenopia, decreasing of visual acuity, headache. The aim of the study was to conduct investigation of direct and consensual pupillary reactions on the flashlight, accommodative‐convergence reaction on a fixed object with the help of elaborated pupillography device before and after instillation of Irifrin 2,5% in both eyes Methods Irifrin 2,5% was applied for diagnoses and treatment of pupillary‐ accommodative system disturbances in 34 раtients aged 7–13 with myopia and hypermetropia. Vision acuity, reserves of accommodation, autorefractometry, pupillography of direct, consensual, pupillary‐ accommodative reactions before and after instillation of Irifrin 2,5% in both eyes were studied. Balance of autonomic nervous system was appreciated by Cerdo index: positive (+) means the prevalence of simpatic; negative (‐) means the prevalence of parasimpatic. It was estimated by following formula: Cerdo index = (1‐D/P) 100 D – diastolic blood pressure; P – number of heart systoles per min; For treatment one drop of Irifrin 2,5% was used once before sleeping in the both eyes during one month. Results Irifrin 2,5% was effective for treatment in all patients with disturbances of accommodation, who had sympathycotonic autonomic balance. During one month after treatment visual acuity increased and normal pupillary‐ accommodative reactions normalized, astenopia and headache disappeared. Conclusion Irifrin 2,5% was effective for diagnoses and treatment of pupillary‐ accommodative system disturbances in раtients. Irifrin 2,5% instillations is recommended for treatment 3‐4 times a year.