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Glaucoma diagnostic accuracy : comparison of RTVue‐100 and Cirrus HD
Author(s) -
FENOLLAND J,
GIRAUD JM,
EL CHEHAB H,
FRANCOZ M,
SENDON D,
MAY F,
RENARD JP
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.f018.x
Subject(s) - cirrus , glaucoma , optometry , ophthalmology , medicine , geology , remote sensing
Purpose To compare diagnostic performance of peripapillary retinal nerve fiber layer and macular complex acquisitions in both Cirrus HD and RTVue OCTs. Methods Observational study. 26 control eyes of 13 patients and 29 glaucomatous eyes of 16 patients were included. Inclusion criteria were : VA>20/25, no retinopathy nor maculopathy, spherical equivalent between ‐6 and 4 diopters, no recent ocular surgery. Acquisition protocols were : optic disc cube and 200x200 macular cube for the Cirrus. RNFL parameters and the macular complex (retinal ganglion cell and inner plexiform ie GCA) in 6 zones were studied. With the RTVue:3D optic disc plus ONH map then macular map. RNFL parameters and macular complex (retinal nerve fiber plus retinal ganglion cell plus inner plexiforme ie GCC). Statistical analysis : normal and glaucomatous population were compared with a Mann‐Whitney test. Area under curve (AUC), sensibility and specificity were calculated for each parameters. Agreement between the 2 OCT for the RNFL was evaluated with a Bland Altman plot Results there was a difference for all the studied parameters between the two populations (u‐test p<0,01). AUC ranges from 0,782 to 0,963. for the Cirrus, the best parameters were GCA inferotemporal (AUC=0,955 Se=88% Sp=91%) and inferior RNFL (AUC=0,963 Se=93 Sp=91%) whereas for the RTVue,it was FLV (AUC=0,942 Se=89%, Sp=92%) and average RNFL (AUC=0,935 Se=85%, Sp=96%). There was no statistical differences when comparing those four AUC. There was a moderate agreement between the RNFL values with a biais of 9 micrometers. Conclusion There is no difference between GCA (Cirrus) and GCC (RTVue) in diagnostic accuracy for glaucoma. Macular parameters have the same performance than peripapillar parameters.