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Asymmetry in hemifield macular thickness as an indicator of early glaucomatous structural or functional progression
Author(s) -
CHEN Y,
KOBAYASHI N,
KOBAYASHI K
Publication year - 2012
Publication title -
acta ophthalmologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.534
H-Index - 87
eISSN - 1755-3768
pISSN - 1755-375X
DOI - 10.1111/j.1755-3768.2012.f014.x
Subject(s) - ophthalmology , glaucoma , medicine , optical coherence tomography , retinal , visual field , absolute deviation , asymmetry , optometry , nerve fiber layer , mathematics , statistics , physics , quantum mechanics
Purpose To evaluate whether asymmetry in macular thickness can serve as an indicator of glaucomatous structural or functional progression utilizing Spectralis spectral domain optical coherence tomography (SD‐OCT). Methods 31 early glaucoma eyes were evaluated in this study. Average macular thickness maps were acquired by posterior pole analysis of SD‐OCT and Macular thickness asymmetry between superior and inferior hemifield was analyzed. 16 eyes were classified as asymmetric and 15 eyes were classified as symmetric. Average macular thickness and circumpapillary retinal never fiber layer (cRNFL) were measured by SD‐OCT while Visual sensitivity loss was determined by mean deviation (MD) using Humphrey Visual Field Analyzer. All examinations were repeated after 6 months. Results In asymmetry group, average macular thickness decreased from 280.8±8.2 to 273.3±7.4μm and cRNFL decreased from 80.2±3.4 to 76.8±3.0μm. Both of them became thinner statistically significantly. In symmetry group, neither average macular thickness nor cRNFL had significant change. Visual sensitivity loss did not get significantly worse in each group. Conclusion Evaluation of asymmetry in macular thickness in early glaucoma eyes may serve as a useful indicator in the progression of glaucomatous changes.